Etymograph

English

metastatic

Metastatic comes from French métastatique, from métastase ‘metastasis’, and ultimately from Proto-Indo-European *steh₂- ‘to stand up’.

  1. Proto-Indo-Europeanc. 4500–2500 BCE*steh₂-1‘to stand up’reconstructed
  2. Proto-Indo-Europeanc. 4500–2500 BCE*stísteh₂ti2‘to be standing up, to be getting up’reconstructed
  3. Proto-Hellenicc. 2200–1600 BCE*hístāmi2‘to stand’reconstructed
  4. Ancient Greekc. 800–300 BCEἵστημι3‘to stand’
  5. Ancient Greekc. 800–300 BCEμεθίστημι4‘to place in another way, change’
  6. Ancient Greekc. 800–300 BCEμετᾰ́στᾰσῐς5‘removing, removal’
  7. Middle Frenchc. 1400–1600metastase5
  8. Frenchc. 1600–presentmétastase6‘metastasis’
  9. Frenchc. 1600–presentstatique7
  10. Frenchc. 1600–presentmétastatique6
  11. Englishearliest quotation 2025metastatic6

attested reconstructed ? uncertain or disputed deepest recorded ancestor

  1. 1 Wiktionary, Proto-Indo-European *stísteh₂ti
  2. 2 Wiktionary, Ancient Greek ἵστημι
  3. 3 Wiktionary, Ancient Greek μεθίστημι
  4. 4 Wiktionary, Ancient Greek μετάστασις
  5. 5 Wiktionary, French métastase
  6. 6 Wiktionary, English metastatic
  7. 7 Wiktionary, French métastatique
  8. Earliest quotation in Wiktionary’s entry: 2025, Dakin Andone: “Three children who are US citizens, including a 4-year-old…”.

Lineage

  1. Proto-Indo-Europeanc. 4500–2500 BCE*steh₂-Wiktionary, Proto-Indo-European *stísteh₂ti‘to stand up’reconstructed
  2. Proto-Indo-Europeanc. 4500–2500 BCE*stísteh₂tiWiktionary, Ancient Greek ἵστημι‘to be standing up, to be getting up’reconstructed
  3. Proto-Hellenicc. 2200–1600 BCE*hístāmiWiktionary, Ancient Greek ἵστημι‘to stand’reconstructed
  4. Ancient Greekc. 800–300 BCEἵστημιWiktionary, Ancient Greek μεθίστημι‘to stand’
  5. Ancient Greekc. 800–300 BCEμεθίστημιWiktionary, Ancient Greek μετάστασις‘to place in another way, change’
  6. Ancient Greekc. 800–300 BCEμετᾰ́στᾰσῐςWiktionary, French métastase‘removing, removal’
  7. Middle Frenchc. 1400–1600metastaseWiktionary, French métastase
  8. Frenchc. 1600–presentmétastaseWiktionary, English metastatic‘metastasis’
  9. Frenchc. 1600–presentstatiqueWiktionary, French métastatique
  10. Frenchc. 1600–presentmétastatiqueWiktionary, English metastatic
  11. Englishearliest quotation 2025metastaticWiktionary, English metastatic. Earliest quotation in Wiktionary’s entry: 2025, Dakin Andone: “Three children who are US citizens, including a 4-year-old…”

Linked words

through Proto-Indo-European *steh₂- ‘to stand up’

post, state, rest, stay, stand, distance, stood, contest, stadium, constitution, instance, establish, stable, stem, stability, instant, substance, testimony, destiny, distant, destination, stud, prostitution, stool, prostitute, substitution, extant, stationary, stamina, stale, stead, distal, attest, stow, testimonial, destitute, astute, oust, stalwart, detest, 139 more

through Proto-Indo-European *stísteh₂ti ‘to be standing up, to be getting up’

consistent, assistant, assistance, assist, resist, insist, consist, persistent, persist, subsistence, desist, armistice, solstice, existentialist, 32 more

through Ancient Greek ἵστημι ‘to stand’

system, histone, hydrostatic, stater, 12 more

Today it means

adj Relating to, or producing metastasis.

Sources

Sources: Wiktionary, “metastatic”; the older steps come from the Wiktionary entries for Proto-Indo-European *stísteh₂ti, Ancient Greek ἵστημι, Ancient Greek μεθίστημι, Ancient Greek μετάστασις, French métastase, French métastatique. By Wiktionary contributors, CC BY-SA 4.0, via kaikki.org (dump of Oct 3 2026); text adapted and restructured. Language periods are conventional ranges, not dates for this word. License.

Etymograph / Proto-Indo-European *steh₂- / metastatic