Etymograph

English

antisense

Antisense comes from Middle English sense ‘meaning, signification’, from Old French sens ‘reason’, and ultimately from Proto-Indo-European *sent- ‘to perceive’.

  1. Proto-Indo-Europeanc. 4500–2500 BCE*sent-1‘to perceive’reconstructed
  2. Proto-Italicc. 1500–700 BCE*sentiō1‘to feel, to sense, to perceive’reconstructed
  3. Latinc. 75 BCE–200 CEsentiō1‘to feel, to sense, to perceive’
  4. Latinc. 75 BCE–200 CEsēnsus1‘perception, feeling, sensation’
  5. Proto-Germanicc. 500 BCE–200 CE*sinnaz1‘sense, perception’reconstructed
  6. Frankishc. 250–700*sinn1reconstructed
  7. Vulgar Latinc. 100–700 CE*sennus1‘sense, reason’reconstructed
  8. Old Frenchc. 842–1400sens1‘reason’
  9. Middle Englishc. 1150–1500sense1‘meaning, signification’
  10. English1500–presentsense1
  11. Englishtodayantisense1

attested reconstructed ? uncertain or disputed deepest recorded ancestor

  1. 1 Wiktionary, English antisense

Lineage

  1. Proto-Indo-Europeanc. 4500–2500 BCE*sent-Wiktionary, English antisense‘to perceive’reconstructed
  2. Proto-Italicc. 1500–700 BCE*sentiōWiktionary, English antisense‘to feel, to sense, to perceive’reconstructed
  3. Latinc. 75 BCE–200 CEsentiōWiktionary, English antisense‘to feel, to sense, to perceive’
  4. Latinc. 75 BCE–200 CEsēnsusWiktionary, English antisense‘perception, feeling, sensation’
  5. Proto-Germanicc. 500 BCE–200 CE*sinnazWiktionary, English antisense‘sense, perception’reconstructed
  6. Frankishc. 250–700*sinnWiktionary, English antisensereconstructed
  7. Vulgar Latinc. 100–700 CE*sennusWiktionary, English antisense‘sense, reason’reconstructed
  8. Old Frenchc. 842–1400sensWiktionary, English antisense‘reason’
  9. Middle Englishc. 1150–1500senseWiktionary, English antisense‘meaning, signification’
  10. English1500–presentsenseWiktionary, English antisense
  11. EnglishtodayantisenseWiktionary, English antisense

A compound of anti- + sense

Proto-Indo-European *h₂ent- ‘forehead’

Proto-Indo-European *h₂énts ‘forehead’

Proto-Indo-European *h₂énti ‘opposite’

Ancient Greek ᾰ̓ντῐ́ ‘over against, opposite’

English anti-

Proto-Indo-European *sent- ‘to feel’

…

Latin sentiō ‘feel, perceive’

Latin sēnsus ‘sensation, feeling, meaning’

Old French sens ‘sense, perception, direction’

Middle English sense ‘meaning’

English sense

Linked words

through Proto-Indo-European *sent- ‘to perceive’

send, sith, 31 more

through Proto-Italic *sentiō ‘to feel, to sense, to perceive’

insensible, 27 more

through Latin sentiō ‘to feel, to sense, to perceive’

sentence, sensitive, consent, consensus, sensible, scent, sensor, sentiment, resent, sensibility, assent, sentient, sentience, 31 more

through Latin sēnsus ‘perception, feeling, sensation’

sensation, sensual, sensuous, sensu, 18 more

through English sense

senseless, 11 more

Today it means

noun The strand of nucleic acid complementary to a strand which codes for an RNA or protein.

Sources

Sources: Wiktionary, “antisense”. By Wiktionary contributors, CC BY-SA 4.0, via kaikki.org (dump of Oct 3 2026); text adapted and restructured. Language periods are conventional ranges, not dates for this word. License.

Etymograph / Proto-Indo-European *sent- / antisense